Stanazolol

One of the key benefits of Stanozolol is its ability to preserve lean muscle mass during a calorie-restricted diet. This property is essential for bodybuilders who wish to retain their muscle gains while reducing body fat. It has gained significant recognition in various sports and bodybuilding circles for its ability to reduce water retention and enhance overall performance. This steroid is particularly valued by those striving to achieve a well-defined and sculpted physique.

Stanazolol have a tissue-selectivity to the androgen receptor, increase anabolism, without an equal increase in androgenic activity.

Stanazolol is a 17α-alkylated steroid. Stanozolol is an oral androgen derived from dihydrotestosterone (DHT) that has a 17-alpha methyl substituent.

Mecanisme of action.

As an AAS, stanazolol is an agonist of the androgen receptor (AR). Unlike testosterone, stanazolol, is not a substrate for 5α-reductase, as it is already 5α reduced, therefore, it is not potentiated in androgenic tissues such as the skin, hair follicles, and prostate gland. This results in less virilizing effects, and a greater ratio of anabolic to androgenic activity.

17α-alkylated steroids, are non-aromatic and do not convert or aromatize to estradiol, which binds to the estrogen receptor (ER), and has no propensity for producing estrogenic effects, such as gynecomastia or fluid retention.

Thus, by using AASs, such as Stanazolol , it will suppress natural testosterone levels, resulting in an of balance of estrogen and testosterone. it is therefore favorable to combine stanazolol with the testosterone

While structural modifications of AAS, will reduce androgenic effects, however, will not completely be removed.

Stanazolol like other AAS, has an anticatabolic effect by interfering with glucocorticoid receptor expression.

Stanozolol Benefits

Increases Lean Body Mass.
Winstrol have high tissue-selectivity for muscle and bone. Androgen receptor stimulation increases muscle protein synthesis and helps in nitrogen retention.

Studies have shown that Stanazolol can increase lean body mass and levels of physical activity. Stanazolol has been shown to be 3x more anabolic than testosterone, with nearly 22% more binding affinity than dihydrotestosterone (DHT).